Kufotokozera Kwachidule:
Nambala ya CAS: 126-07-8
Molecular formula: C17H17ClO6
molekyulu kulemera: 352.77
Chemical kapangidwe:
| Zambiri Zoyambira | |
| Dzina la malonda | Griseofulvin |
| Gulu | kalasi yamankhwala |
| Maonekedwe | ufa woyera mpaka wachikasu-woyera |
| Kuyesa | 99% |
| Alumali moyo | zaka 2 |
| Kulongedza | 25kg/katoni |
| Khalidwe | Sasungunuke m'madzi, sungunuka momasuka mu dimethylformamide ndi tetrachloroethane, sungunuka pang'ono mu anhydrous ethanol ndi methanol |
| Mkhalidwe | Sungani chidebecho chotsekedwa pamalo owuma komanso olowera mpweya wabwino. |
Kufotokozera kwachidule kwa Griseofulvin
Griseofulvin ndi gulu losakhala la polyene antifungal antibiotics;imatha kuletsa kwambiri mitosis ya fungal cell ndikusokoneza kaphatikizidwe ka DNA mafangasi;imathanso kumangirira ku tubulin kuti ipewe kugawanika kwa maselo a mafangasi.Lakhala likugwiritsidwa ntchito pazachipatala kuyambira 1958 ndipo lakhala likugwiritsidwa ntchito kwambiri pochiza matenda oyamba ndi fungus a khungu ndi stratum corneum ndi zotsatira zamphamvu zoletsa pa Trichophyton rubrum ndi Trichophyton tonsorans, etc. Griseofulvin si mankhwala ogwiritsidwa ntchito kwambiri pazachipatala. chithandizo cha matenda oyamba ndi fungus a khungu ndi cuticle, komanso ntchito mu ulimi kupewa ndi kuchiza matenda mafangasi;mwachitsanzo, ali ndi mphamvu yapadera pochiza mtundu wa candidiasis mu apulo womwe ungayambitse matenda panthawi ya pollination.
Zizindikiro za Griseofulvin
Mu mankhwala,mankhwalawa ndi oyenera kuchiza zipere zosiyanasiyana, kuphatikizapo tinea capitis, tinea barbae, tinea thupi, jock itch, phazi tinea ndi onychomycosis.Mitundu yosiyanasiyana ya tinea yotchulidwa imayambitsidwa ndi bowa zosiyanasiyana kuphatikizapo Trichophyton rubrum, Trichophyton tonsorans, Trichophyton mentagrophytes, Fingers Trichophyton, etc., ndi Microsporon audouini, Microsporon canis, Microsporon gypseum ndi Epidermophyton floccosum, etc.Izi sizoyenera kuchiza ngati zing'onozing'ono, matenda amtundu wamba komanso milandu yomwe imatha kuthandizidwa ndi antifungal agents.Griseofulvin siyothandiza pochiza matenda a mitundu yosiyanasiyana ya mafangasi monga Candida, Histoplasma, Actinomyces, Sporothrix mitundu, Blastomyces, Coccidioides, Nocardio ndi Cryptococcus mitundu komanso kuchiza tinea versicolor.
Mu ulimi,mankhwalawa adayambitsidwa koyamba ndi Brian Etal (1951) pofuna kuthana ndi matenda a zomera.Malinga ndi maphunziro apitalo, angagwiritsidwe ntchito kupewa vwende (vwende) choipitsa mpesa, crack kufala matenda, chivwende choipitsa, anthracnose, apulo duwa zowola, apulo ozizira kuvunda, apulo rot, nkhaka downy mildew , sitiroberi imvi nkhungu, mphonda ikulendewera choipitsa. , powdery mildew wa maluwa, chrysanthemums powdery mildew, letesi wowola maluwa, phwetekere choipitsa choyambirira, choipitsa moto wa tulip ndi matenda ena a fungal.
