Kufotokozera Kwachidule:
Nambala ya CAS: 59-05-2
Molecular formula: C20H22N8O5
molekyulu kulemera: 454.45
Chemical kapangidwe:
| Zambiri Zoyambira | |
| Dzina la malonda | Methotrexate |
| Gulu | kalasi yamankhwala |
| Maonekedwe | lalanje-chikasu crystalline ufa. |
| Kuyesa | 99% |
| Alumali moyo | zaka 2 |
| Kulongedza | 25kg/katoni |
| Khalidwe | Wokhazikika, koma wopepuka komanso wa hygroscopic.Zosagwirizana ndi ma asidi amphamvu, oxidizing amphamvu. |
| Mkhalidwe | Sungani pamalo amdima, mumlengalenga, Sungani mufiriji, pansi -20°C |
Kodi Methotrexate ndi chiyani?
Methotrexate imakhudzidwa ndi hydrolysis, oxidation ndi kuwala.Zosasungunuka m'madzi.Methotrexate imawola mumikhalidwe ya acidic kwambiri kapena yamchere.Methotrexate sigwirizana ndi ma oxidizing amphamvu komanso ma asidi amphamvu.
Methotrexate ndi mankhwala omwe amagwiritsidwa ntchito pochiza khansa, yomwe imadziwikanso kuti mankhwala a cytotoxic.Pofuna kuchepetsa cytotoxicity, angagwiritsidwe ntchito molumikizana ndi kashiamu leucovorin.Amagwiritsidwa ntchito makamaka pochiza pachimake khansa ya m'magazi (acute lymphocytic leukemia), khansa ya m'mawere, khansa ya m'mawere, khansa ya mutu ndi khosi, khansa ya m'mafupa, khansa ya m'magazi, kulowetsedwa kwa msana, khansa ya m'mapapo, khansara ya ubereki, khansa ya chiwindi, refractory. psoriasis vulgaris, dermatomyositis, thupi myositis, ankylosing spondylitis kutupa, Crohn a matenda, psoriasis ndi psoriatic nyamakazi, matenda Behcet ndi autoimmune matenda.Methotrexate ndi immuno suppressant ndipo angagwiritsidwe ntchito kuchepetsa njira ya misempha ndi yothandiza kwambiri pochiza synovial kutupa kwa nyamakazi ndipo ndi mankhwala omwe amagwiritsidwa ntchito mobwerezabwereza pochiza matenda a nyamakazi.
Kugwiritsa ntchito kuchipatala
Ndi othandiza pochiza pachimake khansa ya m'magazi ndi bwino efficacy odwala ana.Ili ndi mphamvu yabwino pochiza choriocarcinoma ndi mole yoyipa.Kuwongolera kwa mlingo waukulu ndikothandiza pochiza osteosarcoma, sarcoma ya minofu yofewa, khansa ya m'mapapo, khansa ya testicular, khansa ya m'mawere, ndi khansa ya m'mawere.Zimagwiranso ntchito pochiza khansa ya mutu ndi khosi, khansa ya chiwindi ndi khansa ya m'mimba.Kulowetsedwa kwa arterial kwa mankhwalawa kumakhala ndi mphamvu yabwino pochiza khansa ya mutu ndi khosi komanso khansa ya chiwindi.Komabe, amagwiritsidwa ntchito kawirikawiri pochiza psoriasis ndi psoriasis.
