Kufotokozera Kwachidule:
Nambala ya CAS: 70288-86-7
Molecular formula: C48H74O14
molekyulu kulemera: 875.09
Chemical kapangidwe:
| Zambiri Zoyambira | |
| Dzina la malonda | Ivermectin |
| Gulu | Gulu la Chakudya / Gulu Lodyetsa / Gulu la Mankhwala |
| Maonekedwe | White ufa |
| Kuyesa | 99% |
| Alumali moyo | zaka 2 |
| Kulongedza | 25kg/katoni |
| Mkhalidwe | Malo ozizira ouma |
Kufotokozera kwa Ivermectin
Ivermectin ndi antiparasitic wothandizira pochiza onchocerciasis, kapena "mtsinje khungu".Popeza kuti ivermectin imateteza nyongolotsi yachikulire kuti isatulutse microfilariae, iyenera kuperekedwa kamodzi kapena kawiri pachaka.
Zotsatira za Ivermectin
Ivermectin ndi woyera kapena kuwala chikasu crystalline ufa ndi sungunuka mu methyl mowa, ester ndi onunkhira hydrocarbon koma madzi.Ivermectin ndi mtundu wa mankhwala ophera maantibayotiki omwe amatha kuyendetsa ndikupha pa nematode, tizilombo ndi nthata.Jekeseni ndi troche omwe amapangidwa kuchokera ku ivermectin amagwiritsidwa ntchito makamaka pochiza nematode ya m'mimba, bovine hypodermosis, mphutsi ya ng'ombe, mphutsi yamphuno ya nkhosa, ndi mphere wa nkhosa ndi nkhumba.Kupatula apo, ivermectin imathanso kupezeka pochiza nematodes (ascarid, lungworm) mu nkhuku.Kuphatikiza apo, imathanso kupangidwa kukhala mankhwala ophera tizilombo topha mite, plutella xylostella, caterpillar cabbage, leaf miner, phylloxera ndi nematode omwe ali ndi parasitic muzomera.Chodziwika kwambiri cha mankhwalawa ndi chakuti alibe zotsatirapo zochepa ndipo amatha kuyendetsa ndi kupha tizilombo tambirimbiri mkati ndi kunja panthawi imodzi.
Pharmacology ya Ivermectin
Ivermectin ndi m'gulu la zinthu zomwe zimadziwika kuti avermectines.Awa ndi ma macrocylic lactones opangidwa ndi nayonso mphamvu ya actinomycete, Streptomyces avermitilis.Ivermectin ndi yotakata sipekitiramu wothandizila yogwira motsutsana nematodes ndi arthropods nyama zoweta motero chimagwiritsidwa ntchito mu mankhwala Chowona Zanyama.[1].Mankhwalawa adayambitsidwa koyamba mwa munthu mu 1981. Awonetsedwa kuti ndi othandiza polimbana ndi mitundu yambiri ya nematode monga Strongyloides sp., Trichuris trichiura, Enterobius vermicularis, Ascaris lumbricoides, nyongolotsi za hook ndi Wuchereria bancrofti.Komabe, ilibe mphamvu motsutsana ndi chiwopsezo cha chiwindi ndi cestodes[2].
