Kufotokozera Kwachidule:
Nambala ya CAS: 112811-59-3
Fomula ya mamolekyulu: C19H22FN3O4
molekyulu kulemera: 375.39
Chemical kapangidwe:
| Zambiri Zoyambira | |
| Dzina la malonda | 112811-59-3 |
| Gulu | Gulu la Pharmaceutical |
| Maonekedwe | White to Off-White crystalline ufa |
| Kuyesa | 99% |
| Alumali moyo | zaka 2 |
| Kulongedza | 25kg / ng'oma |
| Kusungirako | Khalani pamalo ozizira owuma |
Mafotokozedwe Akatundu
Gatifloxacin ali m'gulu la mankhwala omwe amadziwika kuti quinolone antibiotics ndipo amagwiritsidwa ntchito pochiza matenda a sinus, mapapo, kapena mkodzo komanso matenda opatsirana pogonana. ndi gatifloxacin monga nseru, vaginitis (kukwiya kapena kutupa kwa nyini), kutsegula m'mimba, mutu, chizungulire, ndi kugunda kwa mtima kosakhazikika.Kawirikawiri, gatifloxacin amagwiritsidwa ntchito mwa anthu omwe samvera mankhwala ena a AOM.
Pakafukufuku wina, gatifloxacin inafanizidwa ndi amoxicillin/clavulanate pochiza otitis media (OM) ndi AOM pakulephera kwamankhwala kwa ana.Makanda ndi ana obwerezabwereza a OM kapena AOM kulephera analandira gatifloxacin kapena amoxicillin/clavulanate. Zotsatira zinasonyeza kuti mankhwala onsewa amaloledwa bwino;Ofufuza anapeza kuti mankhwala a gatifloxacin kamodzi patsiku anali othandiza mofanana ndi amoxicillin/clavulanate kawiri patsiku.
Ntchito Zamankhwala
Sipekitiramuyi imaphatikizapo Acinetobacter spp ndi Aeromonas spp, koma siigwira kwambiri motsutsana ndi Ps.aeruginosa ndi ndodo zina zopanda fermentative Gram-negative.Imagwira kwambiri motsutsana ndi mitundu ya staphylococci yomwe ingatengeke ndi methicillin kuposa mitundu yolimbana ndi methicillin.Imagwiranso ntchito motsutsana ndi Chlamydia, Mycoplasma ndi Legionella spp.ndipo ali ndi zochita zotsutsana ndi ma anaerobes.
Imatengeka pang'onopang'ono ikaperekedwa pakamwa ndipo imagawidwa kwambiri m'thupi lonse m'magulu ambiri amthupi ndi madzi.Theka la moyo wa plasma ndi 6-8 h.Oposa 70% ya mankhwala excreted osasintha mu mkodzo.Chilolezo cha aimpso chimachepetsedwa ndi 57% mwa kulephera kwaimpso pang'ono ndi 77% pakalephera aimpso kwambiri.
Kutalikitsa kwa nthawi ya QTC mwa odwala ena komanso kusokonezedwa ndi matenda a shuga kwapangitsa kuti mankhwalawa achotsedwe m'maiko ambiri kuti agwiritse ntchito mwadongosolo.Gatifloxacin ikugwiritsidwabe ntchito ku North America kokha ngati njira yothetsera maso.
Zotsatira zake
Gatifloxacin imayamwa bwino m'matumbo am'mimba (pafupifupi 100%), komanso kugwiritsa ntchito nthawi yomweyo chakudya cham'mawa, 1050 kcal, sikunakhudze kupezeka kwake.Mlingo wokhazikika ndi 400 mg od ndipo onse amkamwa ndi mtsempha wamagazi amapezeka.
Zotsatira zoyipa
Kuwonjezeka kwa matenda a maso
Kukwiya m'maso
Kupweteka kwamaso
Kusintha kwa kukoma
