Kufotokozera Kwachidule:
Nambala ya CAS: 1405-10-3
Mapangidwe a maselo: C23H48N6O17S
Kulemera kwa maselo: 712.72
Kapangidwe ka Chemical:
| Zambiri Zoyambira | |
| Dzina la malonda | Neomycin sulfate |
| CAS No. | 1405-10-3 |
| Maonekedwe | Ufa Woyera mpaka Wachikasu Pang'ono |
| Gulu | Pharma kalasi |
| Kusungunuka kwamadzi | Zosungunuka m'madzi |
| Kusungirako | 2-8 ° C |
| Shelf Life | 2 Ymakutu |
| Phukusi | 25kg / Drum |
Mafotokozedwe Akatundu
Neomycin sulfate ndi aminoglycoside antibiotic ndi calcium channel protein inhibitor. Neomycin sulfate imamanganso ku prokaryotic ribosomes kuletsa kumasulira ndipo imagwira ntchito motsutsana ndi mabakiteriya a gram-positive ndi gram-negative. Neomycin sulfate inhibits PLC (Phospholipase C) pomanga ku inositol phospholipids. Zimalepheretsanso ntchito ya phosphatidylcholine-PLD ndipo imapangitsa kuti Ca2 + ikhale yolimbikitsa komanso kuyambitsa kwa PLA2 m'mapulateleti aumunthu. Neomycin sulfate imalepheretsa DNase I kuchititsa kuwonongeka kwa DNA. Amagwiritsidwa ntchito popewa kapena kuchiza matenda omwe amayamba chifukwa cha mabakiteriya. Sichigwira ntchito motsutsana ndi matenda oyamba ndi fungus kapena ma virus.
Kugwiritsa ntchito
Neomycin sulfate ndi mankhwala aminoglycoside opangidwa ndi S. fradiae omwe amalepheretsa kumasulira kwa mapuloteni pomanga kumagulu ang'onoang'ono a prokaryotic ribosomes. Imatchinga njira za Ca2+ zokhala ndi mphamvu zamagetsi ndipo ndi inhibitor yamphamvu ya chigoba cha minofu ya sarcoplasmic reticulum Ca2+ kumasulidwa. NEOMYCIN SULFATE yasonyezedwa kuti imalepheretsa kusintha kwa inositol phospholipid, phospholipase C, ndi phosphatidylcholine-phospholipase D ntchito (IC50 = 65 μM). Ndiwothandiza kwambiri polimbana ndi mabakiteriya a gram-positive ndi gram-negative ndipo amagwiritsidwa ntchito poletsa kuipitsidwa ndi mabakiteriya amtundu wa cell.
