Kufotokozera Kwachidule:
Nambala ya CAS: 24390-14-5
Molecular formula: C24H31ClN2O9
molekyulu kulemera: 526.97
Chemical kapangidwe:
| Zambiri Zoyambira | |
| Dzina la malonda | Doxycycline hyclate |
| Gulu | kalasi yamankhwala |
| Maonekedwe | yellow, hygroscopic crystalline ufa |
| Kuyesa | 99% |
| Alumali moyo | zaka 2 |
| Kulongedza | 25kg/katoni |
| Mkhalidwe | kusungidwa pa malo ozizira ndi ouma |
Kufotokozera kwa Doxycycline Hyclate
Doxycycline ndi membala wa gulu la mankhwala a tetracycline, ndipo amagwiritsidwa ntchito pochiza matenda osiyanasiyana. amasungunuka mu njira za alkali hydroxides ndi carbonates.
Doxycycline Hyclate ndi mtundu wa mchere wa hyclate wa doxycycline, ndi anti-spectrum tetracycline antibiotic. Imalepheretsa kaphatikizidwe ka mapuloteni a bakiteriya pomanga ma ribosomes. Doxycycline komanso kusankha linalake ndipo tikulephera anthu masanjidwewo metalloproteinase-8 (MMP-8) ndi MMP-13 pa MMP-1 ndi 50, 60, ndi 5% chopinga, motero, pamene ntchito pa ndende ya 30 μM. Itha kugwiritsidwa ntchito ngati chowongolera pamayendedwe owoneka bwino a jini pomwe mafotokozedwe amadalira kukhalapo (Tet-On) kapena kusapezeka (Tet-Off) kwa doxycycline. Mapangidwe okhala ndi doxycycline akhala akugwiritsidwa ntchito pochiza matenda a bakiteriya komanso kupewa malungo.
Kugwiritsa ntchito Doxycycline hyclate
Doxycycline hyclate ndi membala wa gulu la mankhwala a tetracycline, ndipo amagwiritsidwa ntchito pochiza matenda osiyanasiyana. Amagwiritsidwa ntchito pochiza mauka, rickettsia, mycoplasma ndi matenda ena a spirochete. Amagwiritsidwanso ntchito poletsa matrix metalloproteinases pamlingo wa subantimicrobial. Imalepheretsa matrix metalloproteinases pamlingo wa subantimicrobial.
Doxycycline hyclate ndi yochokera ku oxytetracycline. Zakhala zikugwiritsidwa ntchito kuthetsa Borrelia burgdorferi ndi Anaplasma phagocytophilum m'malo osungira makoswe komanso kuthetsa nkhupakupa za Ixodes scapularis. Ndi wide spectrum inhibitor yomwe imagwiritsidwa ntchito kuletsa matrix metalloproteinases(MMP), monga mtundu wa 1 collagenase mu maphunziro okhudza kuchiritsa mabala ndi kukonzanso minofu.
