Zambiri Zoyambira | |
Dzina la malonda | Daunorubicin hydrochloride |
CAS No. | 23541-50-6 |
Mtundu | Chofiira mpaka chofiira kwambiri |
Fomu | Zolimba |
Kukhazikika: | Kukhazikika |
Kusungunuka | Kusungunuka momasuka m'madzi ndi methanol, kusungunuka pang'ono mu mowa, pafupifupi osasungunuka mu acetone. |
Kusungunuka kwamadzi | Zosungunuka m'madzi (50 mM) |
Kusungirako | Mpweya wozizira, 2-8 ° C |
Shelf Life | 2 Ymakutu |
Phukusi | 25kg / Drum |
Mafotokozedwe Akatundu
Daunorubicin hydrochloride (23541-50-6) ndi antitumor antibiotic yomwe imagwiritsidwa ntchito pochiza acute myeloid leukemias.1?Imapangitsa kuwonongeka kwa DNA mwa intercalation.2?Imapangitsa apoptosis m'maselo osiyanasiyana.3?Kuletsa autophagy ndi chloroquine kumawonjezera daunorubicin. -anachititsa apoptosis mu maselo K562.4?Cell permeable
Kugwiritsa ntchito
Daunorubicin hydrochloride ndi mankhwala a chemotherapy omwe amagwiritsidwa ntchito pochiza mitundu ina ya khansa ya m'magazi ndi khansa zina. Ndi m'gulu la mankhwala omwe amadziwika kuti anthracyclines ndipo amagwira ntchito posokoneza kukula ndi kufalikira kwa maselo a khansa m'thupi.
Daunorubicin hydrochloride nthawi zambiri imaperekedwa kudzera m'mitsempha ndi katswiri wazachipatala m'malo azachipatala. Mlingo ndi kuchuluka kwa chithandizo kumatengera mtundu wa khansa yomwe ikuchiritsidwa, komanso thanzi la wodwalayo komanso momwe angayankhire mankhwalawo.
Ndikofunikira kutsatira mosamala malangizo achipatala oti mulandire daunorubicin hydrochloride komanso kupezeka pamisonkhano yonse yomwe yakonzedwa kuti mukawunikire ndikuwunika panthawi ya chithandizo. Mankhwalawa amatha kukhala ndi zotsatira zoyipa kwambiri, ndipo odwala ayenera kufotokozera zovuta zilizonse kapena kusintha kwa matenda awo ku gulu lawo lachipatala.
Zotsatira zodziwika za daunorubicin hydrochloride zingaphatikizepo nseru, kusanza, kuthothoka tsitsi, komanso kutengeka kwambiri ndi matenda. Zotsatira zoyipa kwambiri monga matenda a mtima ndi kuponderezedwa kwa mafupa amathanso kuchitika ndipo amafuna chithandizo chamankhwala mwachangu.
Monga momwe zimakhalira ndi mankhwala onse a chemotherapy, daunorubicin hydrochloride iyenera kugwiritsidwa ntchito moyang'aniridwa ndi katswiri wodziwa bwino kugwiritsa ntchito mankhwala ochizira khansa. Ndikofunika kukambirana zachipatala kapena mankhwala aliwonse omwe alipo ndi achipatala musanayambe kumwa mankhwala a daunorubicin hydrochloride.