Kufotokozera Kwachidule:
Nambala ya CAS: 50-78-2
Fomula ya mamolekyulu: C9H8O4
molekyulu kulemera:180.16
Chemical kapangidwe:
| Zambiri Zoyambira | |
| Mayina ena | Acetylsalicylic acid |
| Dzina la malonda | Aspirin |
| Gulu | Pharma Grade / Feed Grade |
| Maonekedwe | White crystalline ufa |
| Kuyesa | 99% |
| Alumali moyo | zaka 2 |
| Khalidwe | Kusungunuka pang'ono m'madzi, kusungunuka mu ethanol, ethyl ether, chloroform, sodium hydroxide solution ndi sodium carbonate solution. |
| Kusungirako | Khalani pamalo ozizira owuma |
Mafotokozedwe Akatundu
Aspirin, yemwe amadziwikanso kuti acetylsalicylic acid (ASA), ndi mankhwala omwe amagwiritsidwa ntchito kuchepetsa ululu, kutentha thupi, kapena kutupa. Aspirin ndi mankhwala omwe amagwiritsidwa ntchito kwambiri padziko lonse lapansi.
Ntchito
Acetylsalicylic acid ali antipyretic analgesic, odana ndi kutupa ndi odana ndi rheumatism kwenikweni, ndichifukwa chake nthawi zambiri ntchito malungo, mutu, kupweteka kwa minofu, neuralgia, rheumatic fever, pachimake nyamakazi, gout, etc.; Komanso ali antiplatelet aggregation kwenikweni, ndipo angagwiritsidwe ntchito kupewa ochepa thrombosis, atherosclerosis, zosakhalitsa ubongo ischemia ndi m`mnyewa wamtima infarction; Komanso, asidi acetylsalicylic angagwiritsidwe ntchito pochiza matenda a biliary thirakiti mphutsi ndi phazi wothamanga.
Zochita za pharmacological
Acetylsalicylic acid ndi imodzi mwama antipyretic analgesics, komanso gawo la kuphatikiza mapulateleti. Acetylsalicylic acid m'thupi imakhala ndi mawonekedwe a antithrombotic, imatha kuchepetsa mapangidwe a magazi otchinga m'mitsempha yozungulira, ndikuletsa kuyankha kwa mapulateleti ndi amkati ADP, 5-HT, etc., chifukwa chake kuletsa gawo lachiwiri kuposa loyamba. gawo la kuphatikizika kwa mapulateleti. Limagwirira wa zochita za asidi acetylsalicylic ndi kupanga mapulateleti cyclooxygenase acetylation, motero inhibiting mapangidwe mphete peroxide, ndi TXA2 mapangidwe komanso yafupika. Pa nthawi yomweyo kupanga kupatsidwa zinthu za m`mwazi mapuloteni acetylation, ndi ziletsa kupatsidwa zinthu za m`mwazi nembanemba enzyme, amene amathandiza ziletsa kupatsidwa zinthu za m`mwazi ntchito. Pamene cyclooxygenase imaletsedwa, imakhudza khoma la mtsempha wamagazi lomwe limapangidwa kuti likhale PGI2, ma enzymes opangidwa ndi mapulateleti a TXA2 nawonso kuti aletsedwe; chifukwa chake zingakhudze mapangidwe a TXA2 ndi PGI2 akakhala milingo yayikulu. Oyenera ischemic matenda a mtima, pambuyo percutaneous transluminal coronary angioplasty kapena mtsempha wamagazi bypass kumezanitsa, kupewa kusakhalitsa ischemic sitiroko, m`mnyewa wamtima infarction ndi kuchepetsa chiwerengero cha arrhythmia. Acetylsalicylic acid angagwiritsidwenso ntchito pochiza matenda a biliary thirakiti nyongolotsi ndi phazi la othamanga.
Kugwiritsa ntchito
Ndiwoyamba kugwiritsidwa ntchito, mankhwala odziwika kwambiri komanso odziwika bwino a antipyretic analgesics odana ndi rheumatism, ali ndi mawonekedwe a pharmacological monga antipyretic-analgesic and anti-inflammatory, anti-platelet aggregation ndipo amagwira ntchito mwachangu komanso moyenera. Kuchulukirachulukira kumatha kuzindikirika ndikuchiritsidwa mosavuta, ndi zomwe zimachitika kawirikawiri. Nthawi zambiri amagwiritsidwa ntchito kuzizira, kupweteka mutu, neuralgia, kupweteka kwa mafupa, kupweteka kwa minofu, kutentha kwa thupi, nyamakazi yonyowa kwambiri, nyamakazi ya nyamakazi ndi kupweteka kwa mano, etc. Zolembedwa mu National Essential Medicine List. Acetylsalicylic acid amagwiranso ntchito ngati wapakatikati mwamankhwala ena.
