Timadalira luso lolimba laukadaulo ndipo timapanga umisiri wapamwamba kwambiri kuti tikwaniritse zofuna za Ufa Wabwino Kwambiri 99% Ufa Woyera wa Albendazole, Zida Zanyama Zanyama, Nthawi zonse tikuyembekezera kupanga maubwenzi opambana abizinesi ndi ogula atsopano padziko lonse lapansi.
Timadalira mphamvu zaukadaulo zolimba ndipo timapanga matekinoloje apamwamba kwambiri kuti tikwaniritse zofuna zaChina Albendazole ndi Pharmaceutical Chemical, kampani yathu chimakwirira kudera la 20, 000 lalikulu mamita. Tili ndi antchito opitilira 200, gulu laukadaulo laukadaulo, zokumana nazo zaka 15, luso lapamwamba, khalidwe lokhazikika komanso lodalirika, mtengo wampikisano komanso mphamvu zokwanira zopangira, umu ndi momwe timapangira makasitomala athu kukhala olimba. Ngati muli ndi mafunso, musazengereze kutifunsa.
Kufotokozera
Albendazole (ALBENZA) ndi mankhwala anthelmintic omwe amaperekedwa pakamwa. Piritsi ya Albendazole yophikidwa ili m'gulu la World Health Organisation (WHO) mndandanda wamankhwala ofunikira ngati mankhwala amatumbo anthelminthic ndi antifilarial. Piritsi ya Albendazole idapangidwa ndi SmithKline Animal Health Laboratories ndikuvomerezedwa ndi US Food and Drug Administration (FDA) mu 1996.
Albendazole imatha kupha mazira a chikwapu ndi nyongolotsi komanso kupha pang'ono mazira a Ascaris; Imathanso kuchotsa mitundu yosiyanasiyana ya nematodes parasitizing mkati mwa nyama, ndipo imatha kuchotsa kapena kupha mphutsi za tapeworm ndi cysticerci. Choncho ndi zothandiza pa matenda a hydatid ndi mantha dongosolo (cysticercosis) chifukwa cha matenda a nkhumba nyongolotsi, komanso pochiza mbedza, roundworm, pinworm, nematode trichinella, tapeworm, whipworm ndi stercoralis nematode.
Pharmacodynamics
Albendazole ndi mtundu wa zotumphukira za benzimidazole. Imapangidwa mwachangu mu vivo kukhala sulfoxide, sulfone ndi 2-polyamine sulfone mowa. Itha kuletsa mosasintha komanso mosasinthika kutulutsa kwa shuga m'matumbo a nematodes, zomwe zimapangitsa kuti glycogen iwonongeke; Nthawi yomweyo, imalepheretsanso ntchito ya fumarate reductase, motero imalepheretsa kubadwa kwa adenosine triphosphate, potsiriza kumayambitsa kufa kwa tizilombo toyambitsa matenda.
Mofanana ndi mebendazole, kudzera kuchititsa denaturation wa cytoplasmic microtubules wa matumbo tiziromboti ndi kumanga kwa tubulin, zimayambitsa clogging okhudza maselo ambiri zoyendera, kuchititsa kudzikundikira Golgi endocrine particles; cytoplasm imasungunuka pang'onopang'ono, zomwe zimayambitsa kufa komaliza kwa tizilombo toyambitsa matenda.
Mankhwalawa amatha kupha mazira a nyongolotsi, mazira a pinworm, mazira a ubweya wa ubweya, mazira a tapeworm ndi mazira a cysticercosis ndikupha mazira a Ascaris pang'ono.
Ntchito Wamba
Albendazole ndi mankhwala omwe amagwiritsidwa ntchito pochiza matenda omwe amayamba chifukwa cha tizilombo toyambitsa matenda. Itha kuperekedwa pochiza matenda osowa muubongo (neurocysticercosis) kapena ingaperekedwe pochiza matenda a parasitic omwe amayambitsa kutsekula m'mimba kofunikira (microsporidiosis).
Kugwiritsa Ntchito Zachipatala
Albendazole ali yotakata sipekitiramu ntchito motsutsana matumbo nematodes ndi cestodes, komanso chiwindi flukes Opisthorchis sinensis, Opisthorchis viverrini, ndi Clonorchis sinensis. Yagwiritsidwanso ntchito bwino motsutsana ndi Giardia lamblia. Amagwiritsidwa ntchito kwambiri padziko lonse lapansi pochiza matenda a intestinalnematode. Ndiwothandiza ngati mankhwala amtundu umodzi wa ascariasis, matenda a Hookworm a New and Old World, ndi trichuriasis. Angapo mlingo mankhwala ndi albendazole caneradicate pinworm, threadworm, capillariasis, clonorchiasis, ndi matenda hydatid. Mphamvu ya albendazole motsutsana ndi nyongolotsi (cestodes) nthawi zambiri imakhala yosinthika komanso yosasangalatsa. Ndiwothandizanso pochiza matenda a ubongo ndi msana, makamaka akaperekedwa ndi dexamethasone.Albendazole akulimbikitsidwa kuchiza gnathostomiasis.
Timadalira luso lolimba laukadaulo ndipo timapanga umisiri wapamwamba kwambiri kuti tikwaniritse zofuna za Ufa Wabwino Kwambiri 99% Ufa Woyera wa Albendazole, Zida Zanyama Zanyama, Nthawi zonse tikuyembekezera kupanga maubwenzi opambana abizinesi ndi ogula atsopano padziko lonse lapansi.
Zabwino zabwinoChina Albendazole ndi Pharmaceutical Chemical, kampani yathu chimakwirira kudera la 20, 000 lalikulu mamita. Tili ndi antchito opitilira 200, gulu laukadaulo laukadaulo, zokumana nazo zaka 15, luso lapamwamba, khalidwe lokhazikika komanso lodalirika, mtengo wampikisano komanso mphamvu zokwanira zopangira, umu ndi momwe timapangira makasitomala athu kukhala olimba. Ngati muli ndi mafunso, musazengereze kutifunsa.