Kufotokozera Kwachidule:
Round, Oval, Oblong, Triangle, Diamondi ndi mawonekedwe ena apadera onse alipo.
| Zambiri Zoyambira | |
| Dzina la malonda | Mapiritsi a Folate |
| Mayina ena | Folic Acid Tablet, Activated Folate Tablet, Active Folic Acid Tablet, etc. |
| Gulu | Mlingo wa chakudya |
| Maonekedwe | Monga zofuna za makasitomala Round, Oval, Oblong, Triangle, Diamondi ndi mawonekedwe ena apadera onse alipo. |
| Alumali moyo | Zaka 2-3, malinga ndi momwe sitolo imakhalira |
| Kulongedza | Zochuluka, mabotolo, matuza mapaketi kapena zofunikira zamakasitomala |
| Mkhalidwe | Sungani muzotengera zothina, zotetezedwa ku kuwala. |
Kufotokozera
Zotsatira za kupatsidwa folic acid pa zamoyo makamaka zimaonekera mbali zotsatirazi: kutenga nawo mbali mu kagayidwe chibadwa zakuthupi ndi mapuloteni; zimakhudza ntchito yobereka nyama; zimakhudza katulutsidwe wa kapamba nyama; kulimbikitsa kukula kwa zinyama; ndi kukonza chitetezo cha mthupi.
Methyltetrahydrofolate nthawi zambiri imatanthawuza 5-methyltetrahydrofolate, yomwe imakhala ndi ntchito yopatsa thanzi komanso kuwonjezera kupatsidwa folic acid. 5-Methyltetrahydrofolate ndi chinthu chomwe chimakhala ndi ntchito zogwira ntchito zomwe zimasinthidwa kuchokera ku folic acid kudzera muzochita zingapo zama biochemical m'thupi la munthu. Itha kugwiritsidwa ntchito mwachindunji ndi thupi m'njira zosiyanasiyana zama metabolic kuti thupi lizigwira ntchito bwino, potero limagwira ntchito yolimbitsa thupi.
Ntchito
Folic acid ndi mtundu wa mavitamini a B, omwe amadziwikanso kuti pteroylglutamic acid. 5-methyltetrahydrofolate ndiye gawo lomaliza la metabolism ndikusintha kwa folic acid m'thupi. Chifukwa cha ntchito yake yogwira ntchito, imatchedwanso yogwira ntchito. Folic acid ndi gawo la metabolic la folic acid m'thupi.
Chifukwa mamolekyu a 5-methyltetrahydrofolate amatha kutengeka mwachindunji ndi thupi popanda kutsata njira zovuta zosinthira kagayidwe kachakudya, amapezeka kwambiri m'maselo amthupi. Poyerekeza ndi kupatsidwa folic acid, n'zosavuta kuwonjezera zakudya m'thupi, makamaka kwa amayi omwe amayenera kukonzekera mimba ndi amayi apakati pa nthawi ya mimba.
Folic acid ndi imodzi mwamavitamini ofunikira pakukula ndi kubereka kwa maselo amthupi. Kuperewera kwake kudzakhudza zochitika zakuthupi za thupi la munthu. Zolemba zambiri zanena kuti kuperewera kwa folic acid kumakhudzana mwachindunji ndi neural chubu defects, megaloblastic anemia, cleft mlomo ndi mkamwa, kukhumudwa, zotupa ndi matenda ena.
Neural chubu malformations (NTDs)
Neural chubu malformations (NTDs) ndi gulu la zolakwika zomwe zimachitika chifukwa cha kutsekedwa kosakwanira kwa neural chubu panthawi ya chitukuko cha embryonic, kuphatikizapo anencephaly, encephalocele, spina bifida, ndi zina zotero, ndipo ndi chimodzi mwa zolakwika za mwana wakhanda. Mu 1991, British Medical Research Council inatsimikizira kwa nthawi yoyamba kuti kupatsidwa folic acid supplementation pamaso ndi pambuyo pa mimba kungalepheretse kuchitika kwa NTDs ndi kuchepetsa zochitika ndi 50-70%. Kuteteza kwa kupatsidwa folic acid pa NTDs kumatengedwa kuti ndi chimodzi mwazinthu zosangalatsa kwambiri zomwe zapezedwa chakumapeto kwa zaka za zana la 20.
Megaloblastic anemia (MA)
Megaloblastic anemia (MA) ndi mtundu wa kuchepa kwa magazi m'thupi chifukwa cha kusokonekera kwa kaphatikizidwe ka DNA komwe kumachitika chifukwa cha kusowa kwa folic acid kapena vitamini B12. Zimapezeka kwambiri mwa makanda ndi amayi apakati. Yachibadwa chitukuko cha mwana wosabadwayo amafuna kuchuluka kwa kupatsidwa folic acid nkhokwe mu thupi la mayi. Ngati folic acid yosungidwa yatha panthawi yobereka kapena kumayambiriro kwa mimba, megaloblastic anemia imachitika mwa mwana wosabadwayo ndi mayi. Pambuyo powonjezera kupatsidwa folic acid, matendawa amatha kuchira msanga ndikuchiritsidwa.
Kupatsidwa folic acid ndi kung'ambika milomo ndi mkamwa
Cleft lip and palate (CLP) ndi chimodzi mwa zilema zobadwa nazo. Zomwe zimayambitsa kung'ambika kwa milomo ndi mkamwa sizikudziwikabe. Folic acid supplementation pa nthawi yoyembekezera mimba yatsimikiziridwa kuti imalepheretsa kubadwa kwa ana omwe ali ndi milomo yong'ambika ndi mkamwa.
Matenda ena
Kuperewera kwa folic acid kungayambitse mavuto aakulu kwa amayi ndi ana, monga kupititsa padera chizolowezi, kubadwa msanga, kubadwa kochepa, kusadya bwino kwa mwana wosabadwayo komanso kuchepa kwa kukula. Zolemba zambiri zimati matenda a Alzheimer's, kupsinjika maganizo, ndi kusokonezeka kwa minyewa mwa ana obadwa kumene ndi zotupa zina za muubongo zonse zimagwirizana ndi kuchepa kwa folic acid. Kuphatikiza apo, kusowa kwa kupatsidwa folic acid kungayambitsenso zotupa (khansa ya uterine, khansa ya bronchial, khansa ya m'miyoyo, khansa yapakhungu, ndi zina), matenda a atrophic gastritis, colitis, matenda amtima ndi matenda a cerebrovascular, komanso matenda ena monga glossitis ndi kukula kosauka. Akuluakulu amene akusowa kupatsidwa folic acid ndi kumwa mowa mopitirira muyeso angasinthe dongosolo la matumbo awo mucosa.
Mapulogalamu
1. Amayi pa nthawi yokonzekera mimba ndi mimba yoyambirira.
2. Anthu omwe ali ndi vuto la kuchepa kwa magazi m'thupi.
3. Anthu omwe ali ndi homocysteine okwera.
