Kufotokozera Kwachidule:
Nambala ya CAS:24729-96-2
Fomula ya mamolekyulu: C18H34ClN2O8PS
molekyulu kulemera: 504.96
Chemical kapangidwe:
| Zambiri Zoyambira | |
| Dzina la malonda | Clindamycin Phosphate |
| Gulu | Pharma kalasi |
| Maonekedwe | ufa woyera |
| Kuyesa | 95% |
| Alumali moyo | zaka 2 |
| Kulongedza | 25kg / ng'oma |
| Mkhalidwe | Wokhazikika, koma sungani ozizira. Zosagwirizana ndi oxidizing amphamvu, calcium gluconate, barbiturates, magnesium sulfate, phenytoin, mavitamini a sodium gulu B. |
Kufotokozera
Clindamycin phosphate ndi ester yosungunuka m'madzi ya semisynthetic antibiotic yopangidwa ndi 7 (S) -chloro-m'malo mwa 7 (R) -hydroxyl gulu la kholo la mankhwala, lincomycin. Ndiwochokera ku lincomycin (a lincosamide). Imakhala ndi bacteriostatic action motsutsana ndi ma aerobes a Gram-positive ndi mitundu yambiri ya anaerobic mabakiteriya. Ndi mankhwala apakhungu omwe amagwiritsidwa ntchito pochiza matenda. Izi zingaphatikizepo matenda a kupuma, septicemia, peritonitis ndi matenda a mafupa. Amagwiritsidwanso ntchito pochiza ziphuphu zapakatikati mpaka zowopsa.
Gwiritsani ntchito
Clindamycin phosphate amagwiritsidwa ntchito pamutu pawokha kapena molumikizana ndi benzoyl peroxide pochiza ziphuphu zakumaso vulgaris. Poganizira za ubwino wa mankhwala a topical clindamycin, kuthekera kwa zotsatira zoyipa za GI yokhudzana ndi mankhwalawa ziyenera kuganiziridwa. Chithandizo cha ziphuphu zakumaso vulgaris chiyenera kukhala payekha payekha ndikusinthidwa pafupipafupi kutengera mitundu ya ziphuphu zakumaso zomwe zimakonda kwambiri komanso momwe chithandizo chimathandizira. Mankhwala oletsa tizilombo toyambitsa matenda, kuphatikizapo clindamycin, nthawi zambiri amagwira ntchito pochiza ziphuphu zochepa kapena zochepa. Komabe, kugwiritsa ntchito topical anti-infectives monga monotherapy kungayambitse kukana kwa bakiteriya; kukana kumeneku kumayenderana ndi kuchepa kwa mphamvu yachipatala. Clindamycin yapamutu imathandiza makamaka ikagwiritsidwa ntchito ndi benzoyl peroxide kapena topical retinoids. Zotsatira za kafukufuku wazachipatala zikuwonetsa kuti kuphatikiza mankhwala kumabweretsa kuchepa kwa zotupa zonse za 50-70%.
Clindamycin 2-phosphate ndi mchere wa clincamycin, semisynthetic lincosamide. Mcherewo umakonzedwa ndi kusankha phosphorylation ya 2-hydroxy moiety ya shuga wa clindamycin. Kuyamba kwa phosphate kumapangitsa kusungunuka kwabwino kwa jekeseni. Monga mamembala ena a m'banja la lincosamide, clindamycin 2-phosphate ndi mankhwala opha anthu ambiri omwe amagwira ntchito motsutsana ndi mabakiteriya a anaerobic ndi protozoans. Clindamycin imagwira ntchito pomanga ku 23S ribosomal subunit, kutsekereza kaphatikizidwe ka mapuloteni.
